microLIQUID invites you to Compamed 2017

Posted By J. Garcia / News / biotechnology, microfluidic, microfluidic chip / No hay comentarios

 

 

microLIQUID will be at Compamed 2017 this November 13-16 in Düseldorf, Germany.

 

We will be pleased to invite you to join Hall 8a/F34.1, where we will be demonstrating our latest offerings and technologies (services in mass manufacturing of microfluidic components and automated instruments for the IVD and pharma sector, for example.) and we will have our top product experts on hand to answer your questions.

 

Looking forward to seeing you.

 

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microLIQUID invites you to 2017 AACC Clinical Lab Expo (San Diego)

Posted By Borja Barredo / News / biotechnology, microfluidic chip, microfluidics / No hay comentarios

 

 

Dear partner;

 

microLIQUID will be at the 2017 AACC Clinical Lab Expo this August 1-3 in San Diego, CA.

 

AACC is a global scientific and medical professional organization dedicated to clinical laboratory science and its application to healthcare. Their leadership in education, advocacy and collaboration helps lab professionals adapt to change and do what they do best: provide vital insight and guidance so patients get the care they need.

 

On behalf of our company, if you are attending to AACC, we want to take advantage  to have a meeting with you in order to talk about our common interests.

 

We will be pleased to invite you to join our booth #630,  where we will be showcasing our latest offerings and technologies, and we will have our top product experts on hand to answer your questions.

 

Looking forward to seeing you.

 

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Microfluidics for Chemotaxis : ADVANTAGES

Posted By Borja Barredo / Technology Blog / chemotaxis, microfluidic chip, microfluidics / No hay comentarios

Advantages of using microfluidics for chemotaxis

Advantages of using microfluidics for chemotaxis

Microfluidics: Chemotaxis and ADVANTAGES

it is known microfluidics nowadays is revolutionizing the way the motile behaviour of cells are studied.

It has enabled observations at high spatial and temporal resolution is carefully controlled microenvironments.

Taking into account both of the parts, chemotaxis and microfluidics, there are some advantages when using them two together:
– Presents experimental challenges that are not observed on chemotaxis studies of surface-adherent cells.
– Generate steady, arbitrarily shaped chemical gradients.
– Unique control over the chemoattractant gradient and the migration environment of cells.
– Provide spatial and temporal control over a reproducible chemical environment.
– Enables building well defined and stable chemical gradients at cellular length scales.
– Provide a platform for quantifying cellular responses at cellular and molecular levels.

 

 

 

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Microfluidics Application: What is Chemotaxis?

Posted By Borja Barredo / Technology Blog / chemotaxis, microfluidic chip, microfluidics / No hay comentarios

Chemotaxis with Microfluidics

Chemotaxis with Microfluidics: When an organism moves in response to a chemical stimulus it is said that Chemotaxis has happened

Microfluidics Application: Chemotaxis 

When an organism moves in response to a chemical stimulus it is said that Chemotaxis has happened.

Due to some chemicals that are in the environment the organisms, such as Somatic cells, bacteria, single-cell or multicellular organisms, direct their movements.

When the chemotaxis movements occur toward a higher concentration of the chemical, it is said that is a positive movement.

On the contrary, when the movement is done in the opposite direction, toward the lowest concentration, it is said that is a negative movement.

In addition, if it is nondirectional or randomly directed, the chemotaxis will be called Chemokinesis.

Chemotaxis is done with two independent chemoattractants.

Even if they are independent, we can say that they are interrelated processes-motility and directionality and both of them are regulated by extracellular stimuli.

 

 

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Microfluidics Application: Electrophoresis and Advantages

Posted By Borja Barredo / Technology Blog / electrophoresis, microfluidic chip, microfluidics / No hay comentarios

 

Advantages of using electrophoresis with Microfluidics

Advantages of using electrophoresis with Microfluidics

Electrophoresis using Microfluidics – Main Advantages

Advantages of using electrophoresis with Microfluidics:
1. Improved Diagnosis, simplified diagnostic procedures, faster treatment and results.
2. Simplicity; Fast and easy technique.
3. Low cost material.
4. Reliability.

 

 

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Microfluidics Application: What is Electrophoresis?

Posted By Borja Barredo / Technology Blog / electrophoresis, microfluidic chip, microfluidics / No hay comentarios

Electrophoresis with microfluidics

Electrophoresis with microfluidics:  an analytical method

Electrophoresis and Microfluidics

Electrophoresis is an analytical method which is applied for the separation and characterization of proteins, nucleic acids and subcellular-sized particles such as viruses and small organelles.

 

Its principle is that the charged particles of a sample migrate in an applied electrical field.
Electrophoresis of positively charged particles (cations) is called cataphoresis, and on the other hand, electrophoresis of negatively charged particles (anions) is called anaphoresis.

Electrophoresis is a technique used in laboratories to separate macromolecules based on size.

 

 

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Microfluidics Application: Flow Cytometry and ADVANTAGES

Posted By Borja Barredo / Technology Blog / flow cytometry, Lab on a Chip, microfluidics / No hay comentarios

Flow Cytometer based on Microfluidics and the positive advantages

Flow Cytometer based on Microfluidics and the positive advantagesmicrofluidic microchannels

Flow Cytometry : Advantages of using Microfluidics

Positive aspects about Flow Cytometer based on Microfluidics:

1. To have a high purity and recovery for the sorted cell population.
2. To sort based on an intracellular characteristic in which magnetic beads would not have access.
3. To sort cell labelled with fluorescent probes for nuclear or other intracellular targets.
4. To have information about cell surface molecules.
5. To sort different receptors even if they are low in density.
6. To sort cells according to absence, density or presence of the receptors.

 

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Microfluidics Application: What is Flow Cytometry?

Posted By Borja Barredo / Technology Blog / flow cytometry, Lab on a Chip, microfluidics / No hay comentarios

Flow cytometry is a laser-based technology

Flow cytometry is a laser-based technology used in cell counting, cell sorting, biomarker detection or protein engineering

Flow Cytometry using Microfluidics

Flow cytometry is a laser-based technology used in cell counting, cell sorting, biomarker detection or protein engineering.

By suspending cells and passing these suspending cells by passing them using an electronic detection machine, flow cytometry is done.

This technique allows making simultaneous analysis of the different characteristics of the more than a thousand particles per second.
This technique is usually used in the diagnosis of health disorders, in most of the cases blood cancers, but it is used in many medical trials, such as to sort particles according to their properties or purify populations of interest.

 

 

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Microfluidics Application: Organ on a Chip and the ADVANTAGES

Posted By Borja Barredo / Technology Blog / microfluidic chip, microfluidics, organ on a chip / No hay comentarios

 

Organ on a chip in micrfluidic, great advantages and results

Organ on a chip in microfluidic, great advantages and results

Microfluidic Application: Organ-on-a-Chip

Advantages of Organ-on-a-chip with microfluidics:

1.  3-D tissue structures look like actual organ physiology.
2.  They provide better simulation, which means it is more accurate.
3. For scientist, they can watch the chips in real time and in high resolution.
4. Early effectiveness and safety identification.

 

 

 

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Microfluidics Technologies: What is CNC MICROMACHINING?

Posted By Borja Barredo / Technology Blog / Lab on a Chip, microfluidics, micromachining / No hay comentarios

CNC Micromachining piece for Microfluidics

CNC Micromachining piece for Microfluidics: recent developments in microfabrication enables the integration of hard and soft structures

Microfluidic Manufacturing Technique: CNC Micromachining

CNC Micromachining is defined as the removal of material at micro level.

During the last year the interest over the micro machining technology has increased.

Due to this, every manufacturing and industry segment has started to work, segments such as aerospace, automotive world or medical appliances.

Even , nowadays,  there are still several technical challenges the potential for product miniaturization continues to grow.
The micromachining technologies involves to work with features smaller than 0,001”, that is why, it is necessary to work with accuracy in the 0,0001” or less range, using always cutters smaller than 1/8 or about 3mm. It takes significant speed to effectively use such small-diameter tools, and the machines have to be, as said before, very accurate.

Taking into account the microfluidic field of technology, we can say that micromachining can be used in this field, because recent developments in microfabrication enables the integration of hard and soft structures, making possible to control the microfluidic systems structures. This structures can be applied to drug delivery.

Moreover, there is a manufacturing method which involves laser micromachining for the structure of microfluidic channels in a thin metallic sheet.

It is important to say that some polymers are better to use over silicone when building microfluidic devices because they have biocompatible properties as well as cheapness. Also, using micromachining it is possible to make fewer processing steps than using the conventional way.

 

 

 

 

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